Habenšus, I.; Tomat, E. “Meso-aryl substituents modify the electrochemical profile and palladium(II) coordination of redox-active tripyrrin ligands” Inorg. Chem. Front. 2024, accepted.
Kumar, A.; Thompson, B.; Gautam, R.; Tomat, E.; Huxter, V. "Temperature-Dependent Spin-Driven Dimerization Determines the Ultrafast Dynamics of a Copper(II)-Bound Tripyrrindione Radical" J. Phys. Chem. Lett. 2023, 14, 11268-11273.
Xu, Z.; Sung, Y.-S.; Tomat, E. “Design of tetrazolium cations for the release of antiproliferative formazan chelators in mammalian cells” J. Am. Chem. Soc. 2023, 145, 15197-15206.
Habensus, I.; Ghavam, A.; Curtis, C. J.; Astashkin, A. V.; Tomat, E. “Primary amines as ligands and linkers in complexes of tripyrrindione radicals” J. Porphyrins Phthalocyanines 2023, 27, 1448-1456. DOI: 10.1142/S1088424623501109.
Tomat, E. “Targeting iron to contrast cancer progression” Curr. Opin. Chem. Biol. 2023, 74, 102315.
Tomat, E.; Curtis, C. J.; Astashkin, A. V.; Conradie, J.; Ghosh, A. “Multicenter interactions and ligand field effects in platinum(II) tripyrrin-1,14-dione radicals” Dalton Trans. 2023, 52, 6559-6568.
Wu, W.; Sung, Y.-S.; Tomat, E. “Thiol-Reactive Arylsulfonate Masks for Phenolate Donors in Antiproliferative Iron Prochelators” Inorg. Chem. 2022, 61, 19974-19982.
Sung, Y.-S.; Kerimoglu, B.; Ooi, A.; Tomat, E. “Aroylhydrazone Glycoconjugate Prochelators Exploit Glucose Transporter 1 (GLUT1) to Target Iron in Cancer Cells” ACS Med. Chem. Lett. 2022, 13, 1452-1458.
Cho, B; Swain, A.; Gautam, R; Tomat, E., Huxter, V. "Time-Resolved Dynamics of Stable Open- and Closed-Shell Neutral Radical and Oxidized Tripyrrindione Complexes" Phys. Chem. Chem. Phys. 2022, 24, 15718-15725.
Tomat, E., Curtis, C. J. “Biopyrrin pigments: From heme metabolites to redox-active ligands and luminescent radicals” Acc. Chem. Res. 2021, 54, 4584-4594.
Curtis, C. J.; Astashkin, A. V.; Conradie, J.; Ghosh, A.; Tomat, E. “Ligand-Centered Triplet Diradical Supported by a Binuclear Palladium(II) Dipyrrindione” Inorg. Chem 2021, 60, 12457–12466.
Sung, Y.-S.; Wu, W.; Ewbank, M. A.; Utterback, R. D.; Marty, M. T.; Tomat, E. “Albumin conjugates of thiosemicarbazone and imidazole-2-thione prochelators: Iron coordination and antiproliferative activity” ChemMedChem 2021, 16, 2764-2768. DOI: 10.1002/cmdc.202100278.
Gaur, K.; Pérez Otero, S. C.; Benjamín-Rivera, J. A., Rodríguez, I.; Loza-Rosas, S. A.; Vázquez Salgado, A. M., Akam, E. A., Hernández-Matias, L.; Sharma, R. K.; Alicea, N.; Kowaleff, M.; Washington, A. V.; Astashkin, A. V.; Tomat, E.; Tinoco, A. D. “An iron chelator transmetalative approach to inhibit human ribonucleotide reductase” JACS Au 2021, 1, 865-878. DOI: 10.1021/jacsau.1c00078.
Tomat, E. “Chemistry Discovery: A Service-Learning Outreach Course Produces a Workshop Series for Middle-School Students” J. Chem. Ed. 2020, 97, 4019-4025.
Astashkin, A. V.; Utterback, R. D.; Sung, Y.-S.; Tomat, E. “Iron complexes of an antiproliferative aroyl hydrazone: Characterization of three protonation states by electron paramagnetic resonance methods” Inorg. Chem. 2020, 59, 11377-11384.
Schnetz, M.; Meier, J. K.; Rehwald, C.; Mertens, C; Urbschat, A.; Tomat, E.; Akam, E. A.; Baer, P.; Roos, F. C.; Brüne, B.; Jung, M. “The disturbed iron phenotype of tumor cells and macrophages in renal cell carcinoma influences tumor growth” Cancers 2020, 12, 530.
Curtis, C. J.; Tomat, E. “Heteroleptic palladium(II) complexes of dipyrrin-1,9-dione supported by intramolecular hydrogen bonding” J. Porphyrins Phthalocyanines 2020, 24, 112-120.
Tomat, E. “Propentdyopents: Brief history of a family of dipyrrolic pigments" J. Porphyrins Phthalocyanines 2019, 23, 1265-1272.
Utterback, R. D.; Tomat, E. “Developing Ligands to Target Transition Metals in Cancer” Encyclopedia of Inorganic and Bioinorganic Chemistry 2019, Wiley, DOI: 10.1002/9781119951438.eibc2694.
Swain, A.; Cho, B.; Gautam, R.; Curtis, C. J.; Tomat, E.; Huxter, V. "Ultrafast Dynamics of Tripyrrindiones in Solution Mediated by Hydrogen-Bonding Interactions" J. Phys. Chem. B 2019, 123, 5524-5535.
Jung, M.; Mertens, C.; Tomat, E.; Brüne, B. “Iron as a central player and promising target in cancer progression” Int. J. Mol. Sci. 2019, 20, 273.
Gautam, R.; Petritis, S. J.; Tomat, E. “Redox-switchable cyan fluorescence of a BODIPY analog inspired by propentdyopent pigments” Eur. J. Inorg. Chem. 2019, 68-72.
Gautam, R.; Petritis, S. J.; Astashkin, A. V.; Tomat, E. “Paramagnetism and Fluorescence of Zinc(II) Tripyrrindione: A Luminescent Radical Based on a Redox-active Biopyrrin” Inorg. Chem. 2018, 57, 15240-15246.
Rooker, D. R.; Klyubka, Y.; Gautam, R.; Tomat, E.; Buccella, D. “Peptide-based fluorescent probes for deacetylase and decrotonylase activity: Toward a general platform for real-time detection of lysine deacylation” ChemBioChem 2018, 19, 496-504.
Akam, E. A.; Utterback, R.; Marcero, J. R.; Dailey, H. R.; Tomat, E. “Disulfide-masked iron prochelators: Effects on cell death, proliferation, and hemoglobin production” J. Inorg. Biochem. 2018, 180, 186-193.
Gautam, R.; Astashkin, A. V.; Chang, T. M.; Shearer, J.; Tomat, E. “Interactions of Metal-Based and Ligand-Based Electronic Spins in Neutral Tripyrrindione π Dimers” Inorg. Chem. 2017, 56, 6755–6762.
2016-2013
Mertens, C.; Akam, E. A.; Rehwald, C.; Brüne, B.; Tomat*, E.; Jung*, M. “Intracellular iron chelation modulates the macrophage iron phenotype with consequences on tumor progression” PLoS ONE 2016, 11, e0166164.
Akam, E. A., Tomat*, E. “Targeting iron in colon cancer via glycoconjugation of thiosemicarbazone prochelators” Bioconjugate Chem. 2016, 27, 1807–1812.
Gautam, R.; Chang, T. M.; Astashkin, A. V.; Lincoln, K. M.; Tomat*, E. “Propentdyopent: The scaffold of a heme metabolite as an electron reservoir in transition metal complexes” Chem. Commun. 2016, 52, 6585–6588.
Tomat*, E. “Coordination chemistry of linear tripyrroles: Promises and perils” Comments Inorg. Chem. 2016, 36, 327–342.
Akam, E.; Gautam, R.; Tomat*, E. “Metal-binding effects of sirtuin inhibitor sirtinol” Supramol. Chem. 2016, 28, 108–116.
Gautam, R.; Loughrey, J. J.; Astashkin, A. V.; Shearer, J.; Tomat*, E. “Tripyrrindione as a redox-active ligand: Palladium(II) coordination in three redox states” Angew. Chem. Int. Ed. 2015, 54, 14894–14897.
Gautam, R.; Akam, E. A.; Astashkin, A. V.; Loughrey, J. J.; Tomat*, E. “Sirtuin inhibitor sirtinol is an intracellular iron chelator” Chem. Commun. 2015, 51, 5104–5107.
Akam, E. A.; Chang, T. M.; Astashkin, A. V.; Tomat*, E. “Intracellular reduction/activation of a disulfide switch in thiosemicarbazone iron chelators”Metallomics 2014, 6, 1905–1912.
Chang, T. M.; Sinharay, S.; Astashkin, A. V.; Tomat*, E. “Prodigiosin analogue designed for metal coordination: Stable zinc and copper pyrrolyldipyrrins” Inorg. Chem. 2014, 53, 7518–7526.
Chang, T. M.; Tomat*, E. “Disulfide/thiol switches in thiosemicarbazone ligands for redox-directed iron chelation” Dalton Trans. 2013, 42, 7846–7849.